🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

🔬 Current Disease Focus:

Task Progress: 0%

👥 Active Problem Solvers

🌍 Experts collaborating globally

⚡ Current Task Assignment

🧬 Genetic Analysis

🔄 Matching experts to specific tasks

📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

💊 Treatment Development

Trial Search

Current Search Criteria:

Intervention: Non-statin LMT

Found 12 matching trials

Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 392028

Start Date

2015-11-30

Trial ID

NCT02584504

Treatments Being Tested

Alirocumab Placebo Atorvastatin Non-statin Lipid-Modifying Therapy Diet Alone

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia (ODYSSEY COMBO I)

PHASE3

Alirocumab (SAR236553/REGN727) is a fully human monoclonal antibody that bi...

Status

Completed

Location

Investigational Site Number 840857

Start Date

2012-07

Trial ID

NCT01644175

Treatments Being Tested

Placebo (for alirocumab)Alirocumab Lipid-Modifying Therapy (LMT)

Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwan

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 410001

Start Date

2015-01

Trial ID

NCT02289963

Treatments Being Tested

Placebo (for Alirocumab)Alirocumab Lipid-Modifying Therapy (LMT)

Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)

PHASE3

Primary Objectives: * To demonstrate the superiority of alirocumab in comp...

Status

Completed

Location

Investigational Site Number 840020

Start Date

2015-10-23

Trial ID

NCT02585778

Treatments Being Tested

Alirocumab Placebo Lipid-Modifying Therapy (LMT)Antihyperglycemic Drug

Long-term Safety and Tolerability of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY Long Term)

PHASE3

Alirocumab (SAR236553/REGN727) is a fully human monoclonal antibody that bi...

Status

Completed

Location

Investigational Site Number 840159

Start Date

2012-01

Trial ID

NCT01507831

Treatments Being Tested

Placebo (for alirocumab)Alirocumab Lipid-Modifying Therapy (LMT)

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

PHASE3

Alirocumab (SAR236553/REGN727) is a fully human monoclonal antibody that bi...

Status

Completed

Location

Investigational Site Number 840417

Start Date

2012-07

Trial ID

NCT01623115

Treatments Being Tested

Alirocumab Placebo (for alirocumab)Lipid Modifying Therapy (LMT)

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

PHASE3

This is a randomized, double-blind, placebo-controlled, parallel-group, mul...

Status

Completed

Location

Multiple Locations

Start Date

2012-12

Trial ID

NCT01709500

Treatments Being Tested

LMT (atorvastatin, simvastatin, or rosuvastatin)alirocumab Placebo

Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 840703

Start Date

2013-12-16

Trial ID

NCT02023879

Treatments Being Tested

Alirocumab Placebo (for Alirocumab)Non-statin LMT Diet Alone

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

PHASE4

Primary Objective: To demonstrate the superiority of alirocumab in compari...

Status

Completed

Location

Investigational Site Number 840-163

Start Date

2016-03-15

Trial ID

NCT02642159

Treatments Being Tested

Alirocumab Statins Ezetimibe Fenofibrate Nicotinic acid Omega-3 fatty acids Antihyperglycemic Drug

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 392016

Start Date

2014-03

Trial ID

NCT02107898

Treatments Being Tested

Placebo (for alirocumab)Alirocumab Lipid-Modifying Therapy (LMT)

Previous Next